Supplementing with just one gram of ascorbate (Vitamin C) reduces the level of C-reactive protein (CRP), a biomarker of inflammation that has been shown to be a powerful predictor of cardiovascular disease and diabetes, as much or more than statin drugs. This was shown in a placebo-controlled trial by Berkeley professor emeritus of epidemiology and public health nutrition, Gladys Block.
Block’s study randomized 396 non-smokers to receive 1000mg of ascorbate, 800IU of Vitamin E, or a placebo for two months. Serum C-Reactive Protein (hsCRP) levels were measured before and after the treatment period.
For participants with elevated CRP (>1mg/L), ascorbate lowered CRP by 0.25mg/L compared to placebo. This result is similar to that produced by the use of statin drugs. No CRP reduction benefit was found from the daily doses of Vitamin E, another antioxidant vitamin.
For people who have elevated CRP (but not elevated LDL cholesterol), the data suggest that ascorbate should be investigated as an alternative to statins.
Why lower C-Reactive Protein (CRP)?
Research has shown that a CRP level above 2.4 mg/l has been associated with a doubled risk of a cardiovascular event such as heart attack, stroke or peripheral artery disease compared to levels below 1 mg/l.  Recent research suggests that patients with elevated levels of CRP are at an increased risk of diabetes, hypertension and cardiovascular disease.
CRP Levels and Trans Fats
A study of over 700 nurses showed that those in the highest quartile of trans fat consumption had blood levels of C-reactive protein that were 73% higher than those in the lowest quartile. 
Therefore increased ascorbate consumption along with decreased dietary consumption of trans fatty acids will have a great impact on the risk of diabetes, hypertension and cardiovascular disease.
To reach the levels of Ascorbate reported in the study, you only need to take one Active C Tabs (100) per day. One rounded half-teaspoon of Active C Powder (8oz.) will provide even more of this powerful vitamin in a very cost-effective manner and without the need to swallow a capsule. To lower consumption of trans fatty acids, reduce your intake of fried foods and read food labels to avoid foods that contain partially hydrogenated oils.
1. Pepys MB, Hirschfield GM (2003). “C-reactive protein: a critical update”. J. Clin. Invest. 111 (12): 1805–12. doi:10.1172/JCI18921. PMID 12813013. http://www.jci.org/articles/view/18921.
2. Esther Lopez-Garcia (01 Mar 2005). “Consumption of Trans Fatty Acids Is Related to Plasma Biomarkers of Inflammation and Endothelial Dysfunction”. The Journal of Nutrition 135 (3): 562–566.