(Health Secrets) If you are feeling like you’ve run out of gas, it may be time to revitalize and boost energy with Coenzyme Q10 (CoQ10). Also known as ubiquinone, CoQ10 is an oil-soluble, vitamin-like substance that is absolutely essential for optimum health and longevity.
CoQ10 is naturally found in virtually every cell in the body, primarily in the cellular mitochondria, the furnace of the cell in which food is converted to energy. It is a vital component of the electron transport chain which generates 95 percent of the body’s energy via adenosine triphosphate (ATP). So to boost energy and revitalize, optimal levels of CoQ10 are essential.
CoQ 10 is critical for heart health
Organs with the highest energy requirements, such as the heart, liver, and kidneys, have the highest concentrations of CoQ10. Adequate CoQ10 is essential for cardiovascular health. It is ironic as well as tragic that statin drugs, which are prescribed for reputed heart benefits, actually lower CoQ10 production by up to 40%.
As we age, we lose much of our supply of CoQ10, particularly in the heart. At the age of 80, for example, CoQ10 levels are cut by more than half. CoQ10 benefits and protects the heart in many ways, including helping lower high blood pressure and prevent the oxidation of LDL cholesterol.
The effectiveness and safety of CoQ10 in the treatment of congestive heart failure has been well established by numerous studies. One recent study also found that CoQ10 can improve survival after a cardiac arrest.
CoQ10 is an important antioxidant which inhibits both the initiation and the propagation of lipid and protein oxidation. CoQ10 also regenerates other antioxidants such as vitamin E. One recent study demonstrated that low doses of supplemental CoQ10 reduced oxidation and DNA double-strand breaks.
Low CoQ10 levels have been observed in cancer patients, while treatment with CoQ10 has been shown to be effective against cancer. CoQ10 has also been found to be beneficial for migraine headaches and some studies have indicated that it may help provide better brain health and function.
Lack of CoQ10 can cause Rhabdomyolysis, which is the breakdown of muscle fibers that leads to the release of muscle fiber contents (myoglobin) into the bloodstream. Myoglobin often causes kidney damage. Notably, rhabdomyolysis has often been observed in patients who take statin drugs.
Inadequate CoQ10 levels have been noted in incidences of chronic heart failure, end stage AIDS and other overwhelming illnesses.
In addition to the body, CoQ10 is also found in relatively small amounts in a wide variety of foods, with the highest amounts found in organ meats such as heart, liver and kidney, as well as beef, sardines, mackerel, and peanuts. Other food items with modest amounts of CoQ10 include grapeseed oil, walnuts, hazelnuts, pistachios, parsley, spinach, sesame seeds, olive oil and avocado.
Food sources alone may not be enough for those deficient in CoQ10. To put dietary CoQ10 intake into perspective, one pound of sardines, two pounds of beef, or two and one half pounds of peanuts, provide only 30 mg of CoQ10.
No known toxicity or side effects have been observed in supplemental CoQ10. CoQ10 shows a moderate variability in its absorption, with some patients attaining good blood levels of CoQ10 on 100 mg per day while others require two or three times this amount to attain the same blood level.
Supplementation with CoQ10 has been studied in amounts as high as 3600 mg per day with largely only gastrointestinal side effects observed. The observed safe level (OSL) risk assessment method indicates evidence of safety is strong at intakes up to 1200 mg/day.
For more information: